In this work we report a simple way to assign a single numeric value in a three-dimensional space to a given nucleotide sequence. The method reported allows for theoretical comparisons of naturally occurring nucleotide sequences.

The recent research of Helena Rosenblatt, Hilail Gildin, Arthur Meltzer, and John Scott calls for a reconsideration of Rousseau's stance towards and effect on the natural public law tradition. This reconsideration is especially called for given the persuasive evidence and arguments that these scholars marshal to demonstrate the positive contribution of Rousseau to that tradition and to suggest that his pre-Kantian rational law teaching in the Social Contract is rooted in his post-Hobbesian stance towards natural law, especially in the Second (...) Discourse. The work of these scholars builds upon others, especially on Leo Strauss, Victor Gourevitch, Jean Starobinski, Marc Plattner, Roger Masters and John Charvet, as well as Asher Horowitz, R. A. Leigh, Franz Haymann, and Robert Derathe, and completes the full range of alternative answers to our question. Their contributions are an invaluable scaffolding for fully grasping the issue and for proposing theses that could resolve it. Given the great debt owed to these scholars, the present inquiry begins with an overview and general assessment of their opinions on the issue, which is then followed by a close analysis of the relevant texts of Rousseau, especially the “Preface” to the Second Discourse. (shrink)

To Father Ernest Fortin: [The] highest achievement … of theology's handmaiden is to show that the arguments leveled against divine revelation are not compelling or demonstrably true.1To the extent that we are now in the midst of the so-called “clash of civilizations,” it may be noteworthy that a major controversy—scholarly and journalistic––has emerged over the bearing of Leo Strauss on the defense of the West. This article explores the roots of the controversy as found in his “The Mutual Influence of (...) Theology and Philosophy,” which raises and answers two questions: what is Western Civilization and is it worthy of defense? It is claimed that the very foundation of Western Civilization is constituted at its core by the twin pillars of revelation and Socratic philosophizing; and that the West merits life only if both of its pillars are defendable by reason against rational attack. In what follows, I attempt to trace Strauss's dialectical defense of the West by means of his demonstration of the irrefutability of revelation by reason and the theological-political bearing of this defense. I come to a dual conclusion: the existence of the monotheistic God of revelation is irrefutable by philosophy; yet, the human relevance of revelation, as the guide for a way of life—politically and individually—remains open to challenge by philosophy. Along the way, I also treat the recent research that is in conflict over Strauss's views. (shrink)

Edwards's ontology, derived from his cosmology, harmonized with his theology. All three were derived from his trinitarian model and all three coalesced into a harmonious whole.

In this essay, I examine the ‘Postulates of Linguistics’ chapter of A Thousand Plateaus. In regard to this chapter, I aim to demonstrate something that has remained unrecognised about minor language in Deleuze and Guattari. I aim to show not only the characteristics of Deleuzian speaking in tongues that overlap with Foucaultian speaking-freely and with Derridean speaking-distantly, but also and more importantly, I hope to show how it is possible for us to make a language speak in tongues. Derrida's way (...) of speaking is made only by forming an enunciation that states a self-contradiction, which thereby makes the enunciation imply more than it says. Foucault's way of speaking is made only by forming an enunciation that states the truth directly and loudly, which thereby makes the enunciation do more than it says. And finally, Deleuze way of speaking is made only by forming an enunciation that states a command abstracted from its context, which thereby makes the enunciation proliferate. All three ways of speaking are made not for the benefit of the speaker, but ‘in favour of’ others. And perhaps this speaking ‘in favour of’ others will allow us to come to understand the true meaning of the phrase ‘capitalism and schizophrenia’. (shrink)

Matter and Form explores the relationship between natural science and political philosophy from the classical to contemporary eras, taking an interdisciplinary approach to the philosophic understanding of the structure and process of the natural world and its impact on the history of political philosophy. It illuminates the importance of philosophic reflection on material nature to moral and political theorizing, mediating between the sciences and humanities and making a contribution to ending the isolation between them.

This study investigates the ability of individuals with psychopathy to perform passive avoidance learning and whether this ability is modulated by level of reinforcement/punishment. Nineteen psychopathic and 21 comparison individuals, as defined by the Hare Psychopathy Checklist Revised (Hare, 1991), were given a passive avoidance task with a graded reinforcement schedule. Response to each rewarding number gained a point reward specific to that number (i.e., 1, 700, 1400 or 2000 points). Response to each punishing number lost a point punishment specific (...) to that number (i.e., the loss of 1, 700, 1400 or 2000 points). In line with predictions, individuals with psychopathy made more passive avoidance errors than the comparison individuals. In addition, while the performance of both groups was modulated by level of reward, only the performance of the comparison population was modulated by level of punishment. The results are interpreted with reference to a computational account of the emotional learning impairment in individuals with psychopathy. (shrink)

Recently, there has been renewed interest in the search for low-mass magnetic monopoles. At the University of Oklahoma we are performing an experiment (Fermilab E882) using material from the old D0 and CDF detectors to set limits on the existence of Dirac monopoles of masses of the order of 500 GeV. To set such limits, estimates must be made of the production rate of such monopoles at the Tevatron collider, and of the binding strength of any such produced monopoles to (...) matter. Here we sketch the still primitive theory of such interactions, and indicate why we believe a credible limit may still be obtained. On the other hand, there have been proposals that the classic Euler–Heisenberg Lagrangian together with duality could be employed to set limits on magnetic monopoles having masses less than 1 TeV, based on virtual, rather than real processes. The D0 collaboration at Fermilab has used such a proposal to set mass limits based on the nonobservation of pairs of photons each with high transverse momentum. We critique the underlying theory, by showing that the cross section violates unitarity at the quoted limits and is unstable with respect to radiative corrections. We therefore believe that no significant limit can be obtained from the current experiments, based on virtual monopole processes. (shrink)

Growing evidence suggests mothers invest more in girls than boys and fathers more in boys than girls. We develop a hypothesis that predicts preference for girls by the parent facing more resource constraints and preference for boys by the parent facing less constraint. We test the hypothesis with panel data from the Tsimane’, a foraging-farming society in the Bolivian Amazon. Tsimane’ mothers face more resource constraints than fathers. As predicted, mother’s wealth protected girl’s BMI, but father’s wealth had weak effects (...) on boy’s BMI. Numerous tests yielded robust results, including those that controlled for fixed effects of child and household. (shrink)

Previous research addressing the association between leisure and happiness has given rise to the hypothesis that informal social activities might contribute more to happiness than solitary activities. In the current study, we tested how the two types of leisure—social and solitary—contribute to a person’s subjective sense of well-being. For the empirical estimate, we used four consecutive quarters of data collected from 533 people over the age of 16, from 13 Tsimane’ hunter-farmer villages in the Bolivian Amazon. Results suggest that only (...) social, not solitary, leisure has a positive and statistically significant association with subjective well-being. The association between solitary leisure and subjective well-being was negligible or negative. Future research should focus on emic definitions of social and solitary time, for solitary time might not always be equivalent to leisure and productive group activities might substitute for social leisure. (shrink)

Background To describe the preferences for disclosure of individual biomarker results among mothers participating in a longitudinal birth cohort. Methods We surveyed 343 mothers that participated in the Health Outcomes and Measures of the Environment Study about their biomarker disclosure preferences. Participants were told that the study was measuring pesticide metabolites in their biological specimens, and that the health effects of these low levels of exposure are unknown. Participants were asked whether they wanted to receive their results and their child's (...) results. In addition, they were asked about their preferred method (letter vs in person) and format (more complex vs less complex) for disclosure of results. Results Almost all of the study participants wanted to receive their individual results (340/343) as well as their child's results (342/343). However, preferences for receiving results differed by education level. Mothers with less than a college degree preferred in-person disclosure of results more often than mothers with some college education or a college degree (34.3% vs 17.4% vs 7.9%, p<0.001). Similarly, mothers with less than a college education preferred a less complex disclosure format than mothers with some college education or a college degree (59.7% vs 79.1% vs 86.3%, p<0.0001). Conclusion While almost all study participants preferred to receive results of their individual biomarker tests, level of education was a key factor in predicting preferences for disclosure of biomarker results. To ensure effective communication of this information, disclosure of biomarker results should be tailored to the education level of the study participants. (shrink)

History and chronicle, by B. Croce.--History as a system, by J. Ortega y Gasset.--The idea of history, by R. G. Collingwood.--The historian's purpose; history and metahistory, by A. Bullock.--What are historians trying to do? By H. Pirenne.--What are historical facts? By C. Becker.--The concept of scientific history, by I. Berlin.--Reason in history, by G. W. F. Hegel.--The hedgehog and the fox, by I. Berlin.--What is history? By E. H. Carr.--Faith and history, by R. Niebuhr.--The world and the west, by A. (...) Toynbee.--Debates with historians, by P. Geyl.--Has history any meaning? By K. R. Popper.--Historical inevitability, by I. Berlin.--On fortune and misfortune in history, by J. Burckhardt.--Selected readings (p. 179-181). (shrink)

1. Reference and modality by W. V. O. Quine.--2. Modality and description by A. F. Smullyan.--3. Extensionality by R. B. Marcus.--4. Quantification into causal contexts by D. Føllesdal.--5. Semantical considerations on modal logic by S. A. Kripke.--6. Essentialism and quantified modal logic by T. Parsons.--7. Reference, essentialism, and modality by L. Linsky.--8. Quantifiers and propositional attitudes by W. V. O. Quine.--9. Quantifying in by D. Kaplan.--10. Semantics for propositional attitudes by J. Hintikka.--11. On Carnap's analysis of statements of assertion and (...) belief by A. Church.--Bibliography (p. [173]-175). (shrink)